This is a prospective randomized controlled trial in which patients with small breast cancer (T<2 cm), with a negative preoperative assessment of the axilla (ultra-sound with FNAC in presence of doubtful findings) will be randomized into two treatment arms: Moreover, to date the impact of the prognostic information of axillary lymph node status in the decision-making process is less important than in the past as the adjuvant treatment is more and more tailored on the biological features of the disease rather than on the risk of recurrence. no further axillary surgery in presence of positive SLN did not show any difference in term of overall and disease-free survival. Recent data from a prospective randomized trial which compared axillary dissection vs. In fact, it is well known that removal of lymph nodes is performed with staging purposes and to improve regional control but not with curative intent. The evident trend of breast cancer treatment is going towards minimizing axillary surgery, even in presence of involvement of the sentinel lymph node (SLN). Sentinel lymph node biopsy (SLNB) is the standard approach for axillary staging in patients with breast cancer worldwide. to verify whether, in presence of a negative preoperative axillary assessment, the patients' quality of life can be improved by a less invasive surgical procedure.to verify whether, in presence of a negative preoperative axillary assessment, the decision on adjuvant medical treatment can be taken according only to the biology of the tumour without the prognostic information achieved by SLNB on the nodal status.to verify whether, in presence of a negative preoperative axillary assessment, SLN can be spared.The aims of this prospective randomized study are:
pre-operative imaging of the axilla can identify patients with clinically relevant nodal burden.avoiding axillary surgery does not worsen the outcome of patients with small breast cancer the absence of the pathological information on the risk of recurrence given by nodal status is not worsening outcome of these patients.Why Should I Register and Submit Results?.
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